Acid cyclization of amino-substituted heterocycles. Synthesis of 1,3-dioxo- pyrrolo[3,4-c]- and thieno[3,4-c]isoquino- lines and cinnolines

作者：Zinchenko S Yu; Efimenko R A; Suikov S Yu; Kobrakov K I; Bogza S L^*

来源：Chemistry of Heterocyclic Compounds, 2009, 45(3): 365-369.

DOI：10.1007/s10593-009-0262-2

• aminomaleimide
• 3-aminothiophene
• carbonyl compounds
• cyclization

The reaction of 3-amino-4-(3,4-dimethoxyphenyl)maleimide and the methyl esters of 3-amino-4-(3,4-dimethoxyphenyl)-5-R-thiophene-2-carboxylic acids with carbonyl compounds and nitrous acid has been investigated. Dioxopyrrolo[3,4-c]- and thieno[3,4-c]isoquinolines and cinnolines were obtained.

• 出版日期2009-3