Age differences in head motion and estimates of cortical morphology

作者：Madan Christopher R^*

来源：PeerJ, 2018, 6: e5176.

DOI：10.7717/peerj.5176

• Head motion
• Cortical structure
• Fractal dimensionality
• Age
• Cortical thickness
• Gyrification
• Cortical morphology
• Movie watching
• BMI

Cortical morphology is known to differ with age, as measured by cortical thickness, fractal dimensionality, and gyrification. However, head motion during MRI scanning has been shown to influence estimates of cortical thickness as well as increase with age. Studies have also found task-related differences in head motion and relationships between body-mass index (BMI) and head motion. Here I replicated these prior findings, as well as several others, within a large, open-access dataset (Centre for Ageing and Neuroscience, CamCAN). This is a larger dataset than these results have been demonstrated previously, within a sample size of more than 600 adults across the adult lifespan. While replicating prior findings is important, demonstrating these key findings concurrently also provides an opportunity for additional related analyses: critically, I test for the influence of head motion on cortical fractal dimensionality and gyrification; effects were statistically significant in some cases, but small in magnitude.

• 出版日期2018-7-27