Mouse Resource Browser-a database of mouse databases

作者：Zouberakis Michael; Chandras Christina; Swertz Morris; Smedley Damian; Gruenberger Michael; Bard Jonathan; Schughart Klaus; Rosenthal Nadia; Hancock John M; Schofield Paul N; Kollias George; Aidinis Vassilis^*

来源：Database-The Journal of Biological Databases and Curation, 2010, baq010.

DOI：10.1093/database/baq010

The laboratory mouse has become the organism of choice for discovering gene function and unravelling pathogenetic mechanisms of human diseases through the application of various functional genomic approaches. The resulting deluge of data has led to the deployment of numerous online resources and the concomitant need for formalized experimental descriptions, data standardization, database interoperability and integration, a need that has yet to be met. We present here the Mouse Resource Browser (MRB), a database of mouse databases that indexes 217 publicly available mouse resources under 22 categories and uses a standardised database description framework (the CASIMIR DDF) to provide information on their controlled vocabularies (ontologies and minimum information standards), and technical information on programmatic access and data availability. Focusing on interoperability and integration, MRB offers automatic generation of downloadable and re-distributable SOAP application-programming interfaces for resources that provide direct database access. MRB aims to provide useful information to both bench scientists, who can easily navigate and find all mouse related resources in one place, and bioinformaticians, who will be provided with interoperable resources containing data which can be mined and integrated.
Database URL: http://bioit.fleming.gr/mrb

• 出版日期2010