ASSOCIATION BETWEEN MACULAR PERFUSION AND PHOTORECEPTOR LAYER STATUS IN DIABETIC MACULAR EDEMA

作者：Benitez Herreros Javier^*; Lopez Guajardo Lorenzo; Camara Gonzalez Cristina; Vazquez Blanco Miguel; Castro Rebollo Maria

来源：Retina-The Journal of Retinal and Vitreous Diseases, 2015, 35(2): 288-293.

DOI：10.1097/iae.0000000000000299

• diabetic macular edema
• external limiting membrane
• foveal avascular zone
• inner and outer segment junction band
• inner segment ellipsoid band
• macular perfusion
• photoreceptor layer status

Purpose: To evaluate the relationship between the photoreceptor layer status (inner segment ellipsoid band and external limiting membrane) and the foveal avascular zone size, as a result of macular perfusion, in patients with diabetic macular edema.
Methods: This observational case series study included 151 eyes of 118 patients with naive diabetic macular edema. The length of the disrupted photoreceptor layer was assessed by optical coherence tomography. The foveal avascular zone diameter was measured on fluorescein angiogram.
Results: No significant association was found between the foveal avascular zone size and the mean lengths of the disrupted inner segment ellipsoid band nor the external limiting membrane in patients with naive diabetic macular edema.
Conclusion: Macular ischemia, which lengthens the distance from the perifoveal vessels to the center of the fovea and may disrupt the normal flow of nutrients by simple diffusion to the photoreceptor line, does not seem to influence on inner segment ellipsoid band nor external limiting membrane integrity. Future studies may evaluate the effect of choroidal vascularization on the photoreceptor layer status to enhance the knowledge about the photoreceptor layer nutrients source.

• 出版日期2015-2