An 11-year and 10-month-old girl with purpura and chest pain

作者:Chen Pei Hsuan; Chiang Bor Luen; Lu Meng Yao; Yang Yao Hsu*
来源:Journal of Microbiology, Immunology, and Infection, 2014, 47(5): 438-440.
DOI:10.1016/j.jmii.2012.06.011

摘要

Mucosa-associated lymphoid tissue lymphoma (MALToma) is a type of B-cell lymphoma. Case reports of childhood thymic MALToma and its association with vasculitis are rarely found in the related literature. Herein, we present a report of an 11-year and 10-month-old girl who was initially diagnosed with cutaneous vasculitis characterized by nonthrombocytopenic palpable purpura, positive antinuclear antibody and anti-SSA (Ro) antibody. Eight months later, a thymic mediastinal mass was found. Surgical excision was performed and results of pathological analysis revealed an extranodal marginal zone CD20(+) B-cell MALToma. Benign response to the chemotherapeutic regimen of Berlin Frankfurt Munster group NHL-BFM 90 R2 without relapse was noted in 2 years of follow-up. For the first time, our case demonstrated some clinical evidence of the association between vasculitis and childhood MALToma.

  • 出版日期2014-10

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