Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials

作者：Kelley George A^*; Kelley Kristi S; Roberts Susan; Haskell William

来源：Clinical Nutrition, 2012, 31(2): 156-167.

DOI：10.1016/j.clnu.2011.11.011

• Exercise
• Diet
• Cholesterol
• Lipids
• Lipoproteins
• Meta-analysis

Objective: Given that previous studies have reached conflicting conclusions regarding the effects of diet (D), aerobic exercise (E) or both (DE) on blood lipid and lipoprotein concentrations in adults, the meta-analytic approach was used to address this issue. %26lt;br%26gt;Data sources: Nine electronic databases, cross-referencing, and expert review. %26lt;br%26gt;Study selection: Randomized controlled trials %26gt;= 4 weeks that included a D, E. DE and control (C) group in adults %26gt;= 18 years of age and in which data for one or more of the following were available: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG). %26lt;br%26gt;Data extraction: Dual data extraction by the first two authors. %26lt;br%26gt;Statistical analysis: Random-effects models as well as mixed-effects models for between-group differences. %26lt;br%26gt;Results: Seven-hundred and eighty-eight men and women from 6 studies were included. Non-overlapping 95% confidence intervals were observed for D and DE with respect to lowering TC, LDL-C and TG while reductions in E were limited to TG. No significant changes in HDL-C were observed. When compared to E, reductions in TC and LDL-C were greater for D and DE (p %26lt; 0.05 for all). %26lt;br%26gt;Conclusions: Diet, especially DE, are superior to E for improving selected lipids and lipoproteins in adults.

• 出版日期2012-4