A facile synthesis of 2-aryl-4-(indol-3-yl)-4H-chromenes using amberlyst-15 as an efficient recyclable heterogeneous catalyst

作者：Guha Chayan; Sepay Nayim; Mallik Asok K^*

来源：Monatshefte fur Chemie, 2015, 146(8): 1349-1354.

DOI：10.1007/s00706-014-1401-8

• 2-Aryl-4-(indol-3-yl)-4H-chromenes
• Heterogeneous catalysis
• Michael addition
• Cyclization

Starting from 2-hydroxychalcones and indoles, a facile synthesis of 2-aryl-4-(indol-3-yl)-4H-chromenes has been achieved by use of amberlyst-15, a sulfonated polystyrene resin, as a recyclable heterogeneous catalyst. The methodology involves a domino sequence of Michael addition, cyclization, and dehydration.

• 出版日期2015-8