Base-Free Iridium-Catalyzed Hydrogenation of Esters and Lactones

作者：Brewster Timothy P; Rezayee Nomaan M; Culakova Zuzana; Sanford Melanie S; Goldberg Karen I

来源：ACS Catalysis, 2016, 6(5): 3113-3117.

DOI：10.1021/acscatal.6b00263

• ester
• hydrogenation
• acid
• homogeneous catalysis
• iridium

Half-sandwich iridium bipyridine complexes catalyze the hydrogenation of esters and lactones under base-free conditions. The reactions proceed with a variety of ester and lactone substrates. Mechanistic studies implicate a pathway involving rate-limiting hydride transfer to the substrate at high pressures of H-2 (>= 50 bar).

• 出版日期2016-5