alpha-Fluorohydrazones as useful precursors in nucleophilic substitutions

作者:Yunoki Ryota; Yajima Atsushi; Taniguchi Tsuyoshi*; Ishibashi Hiroyuki
来源:Tetrahedron Letters, 2013, 54(31): 4102-4105.
DOI:10.1016/j.tetlet.2013.05.110

摘要

C-F bonds on alpha-fluorohydrazones can be substituted with a wide range of nucleophiles with the aid of mild bases. The present reaction shows that alpha-fluorohydrazones can be useful building blocks in synthetic chemistry.