Analysis on prognostic factors of patients with ruptured intracranial aneurysms

作者：Qin, Shiqiang; Sun, Xiaoyan; Hui, Peiquan; Li, Jinlei; Wang, Zengwu^*

来源：International Journal of Clinical and Experimental Medicine, 2017, 10(1): 1303-1308.

• Ruptured intracranial aneurysm
• risk factor
• prognosis

Background: Intracranial aneurysm (IA) is a common vascular disease which causes neoplastic hyperplasia of cerebral vessels. It is very important to study relevant factors that influence the prognosis of patients with ruptured intracranial aneurysm to guide the clinical treatment of IA. Methods: This study made a retrospective analysis on data of 580 patients with ruptured IA. To screen risk factors that related to the prognosis of ruptured IA, univariate analysis of variance by Chi(2) test or Wilcoxon test, and multivariable logistic by multiple logistic regression model were carried out. According to the Glasgow Outcome Scale (GOS) scored, the surgical outcomes were also evaluated. Results: The univariate analysis results showed that Age, headache symptoms, Hunt-Hess classification, onset time of surgery, and surgical approach were the risk factors related to the prognosis of patients with ruptured IA. Multivariable logistic regression analysis results showed that the age (P=0.021), Hunt-Hess classification (P=0.002). Onset time of surgery (P=0.019) and surgical approach (P <= 0.003) were the independent risk factors. Conclusions: The ultimate outcome of the patients with ruptured intracranial aneurysm depend on clinical judgement including accurate comprehensive analysis, the best surgical time, the right surgical method.

• 出版日期2017
• 单位潍坊市人民医院