Mouse Models of Inherited Cancer Syndromes

作者:Jahid Sohail; Lipkin Steven*
来源:Hematology-Oncology Clinics of North America, 2010, 24(6): 1205-+.
DOI:10.1016/j.hoc.2010.08.011

摘要

Animal models of cancer have been instrumental in understanding the progression and therapy of hereditary cancer syndromes The ability to alter the genome of an individual mouse cell in both constitutive and inducible approaches has led to many novel insights into their human counterparts In this review knockout mouse models of inherited human cancer syndromes are presented and insights from the study of these models are highlighted

  • 出版日期2010-12