Robo3: The Road Taken

作者：Beamish Ian V; Kennedy Timothy E^*

来源：Developmental Cell, 2015, 32(1): 3-4.

DOI：10.1016/j.devcel.2014.12.021

Although axon guidance mechanisms are well conserved across the animal kingdom, neuronal circuit complexity increases dramatically in evolution. Reporting recently in Neuron, Zelina et al. (2014) uncover mammalian-specific changes in Robo3 that result in a switch from repellent to attractive signaling and may have contributed to increased mammalian circuit complexity.

• 出版日期2015-1-12
• 单位McGill