A randomized study of three interventions for aspiration of thin liquids in patients with dementia or Parkinson's disease

作者：Logemanin Jeri A^*; Gensler Gary; Robbins JoAnne; Lindblad Anne S; Brandt Diane; Hind Jacqueline A; Kosek Steven; Dikernan Karen; Kazandiian Marto; Grarnigna Gary D; Lundy Donna; McGarvey Toler Susan; Gardner Patricia J Miller

来源：Journal of Speech, Language, and Hearing Research, 2008, 51(1): 173-183.

DOI：10.1044/1092-4388(2008/013)

• dementia
• Parkinson's disease
• aspiration
• thickened liquids
• posture

Purpose: This study was designed to identify which of 3 treatments for aspiration on thin liquids-chin-down posture, nectar-thickened liquids, or honey-thickened liquids-results in the most successful immediate elimination of aspiration on thin liquids during the videofluorographic swallow study in patients with dementia and/or Parkinson's disease.
Method: This randomized clinical trial included 711 patients ages 50 to 95 years who aspirated on thin liquids as assessed videofluorographically. All patients received all 3 interventions in a randomly assigned order during the videofluorographic swallow study.
Results: immediate elimination of aspiration on thin liquids occurred most often with honey-thickened liquids for patients in each diagnostic category, followed by nectar-thickened liquids and chin-down posture. Patients with most severe dementia exhibited least effectiveness on all interventions. Patient preference was best for chin-down posture followed closely by nectar-thickened liquids.
Conclusion: To identify best short-term intervention to prevent aspiration of thin liquid in patients with dementia and/or Parkinson's disease, a videofluorographic swallow assessment is needed. Evidence-based practice requires taking patient preference into account when designing a dysphagic patient's management plan. The longer-term impact of short-term prevention of aspiration requires further study.

• 出版日期2008-2
• 单位西北大学