A short synthesis of nonracemic iodocyclohexene carboxylate fragment for kibdelone and congeners

作者：Endoma Arias Mary Ann A; Hudlicky Tomas^*

来源：Tetrahedron Letters, 2011, 52(49): 6632-6634.

DOI：10.1016/j.tetlet.2011.10.005

• Microbial dihydroxylation
• Markovnikov hydration
• Kibdelones
• Nonracemic

A previously reported nonracemic iodocyclohexene carboxylate intermediate used in the asymmetric preparation of kibdelone C and its congeners was prepared in two synthetic steps from the product of microbial dihydroxylation of methyl 2-iodobenzoate.

• 出版日期2011-12-7