Anti-oxidant, hypoglycemic and anti-hyperglycemic properties of Syzygium calophyllifolium

作者:Chandran Rahul; Sathyanarayanan Saikumar; Rajan Murugan; Kasipandi Muniyandi; Parimelazhagan Thangaraj*
来源:Bangladesh Journal of Pharmacology, 2015, 10(3): 672-680.
DOI:10.3329/bjp.v10i3.23361

摘要

The article discusses anti-oxidant oral glucose tolerance and anti-hyperglycemic potentials of S. calophyllifolium. Extracts from successive solvent extraction were tested for the total phenolic, tannin, flavonoid content and free radical scavenging property using DPPH, ABTS(+), phosphomolyb-denum, FRAP, superoxide and metal chelating assays. Ethyl acetate extract of bark responded well against DPPH (IC50 4.13), ABTS(+) (36832.29 mu M TE/ g extract), phosphomolybdenum (100.4 g AAE/100g extract), superoxide and metal ion radicals. The methanol extract of bark was also found as an effective radical scavenger. The leaf methanol extract also showed significant anti-oxidant ability. The bark methanol extract could potentially reduce the blood glucose level in glucose loaded and diabetic rats. The immense anti-oxidant potential of S. calophyllifolium leaf and bark extracts could be taken as a good source of natural anti-oxidant supplement in food to defend oxidative stress related disorders like diabetes.

  • 出版日期2015