System maps for retention of small neutral compounds on a biphenylsiloxane-bonded silica stationary phase in reversed-phase liquid chromatography

作者：Atapattu Sanka N; Poole Colin F^*; Praseuth Mike B

来源：Journal of Chromatography A, 2016, 1478: 68-74.

DOI：10.1016/j.chroma.2016.11.059

• Reversed-phase liquid chromatography
• Retention
• Selectivity Solvation parameter model
• System maps
• Retention mapping
• Column characterization

The system constants of the salvation parameter model are used to prepare system maps for the retention of small neutral compounds on a biphenylsiloxane-bonded superficially porous silica stationary phase (Kinetex Biphenyl) for aqueous-organic solvent mobile phases containing 10-70% (v/v) methanol or acetonitrile. The retention properties of the biphenylsiloxane-bonded phase are shown to be complementary to an octadecylsiloxane-bonded silica (Kinetex C-18) and a pentafluorophenyipropylsiloxane-bonded silica stationary phases (Discovery HS F5). The retention properties of the Kinetex Biphenyl column are similar to an ether-linked phenylpropylsiloxane-bonded silica phase (Synergi Polar RP) with only small differences in relative retention.

• 出版日期2016-12-23