Annular Elastolytic Giant Cell Granuloma Associated with Temporal Arteritis Leading to Blindness

作者：Shoimer Ilya; Wismer Judy^*

来源：Journal of Cutaneous Medicine and Surgery, 2011, 15(5): 293-297.

DOI：10.2310/7750.2011.10042

Background: Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous disorder characterized by giant cells in the dermis phagocytosing damaged elastin fragments.
Objective: We report a case of a 71-year-old man presenting with erythematous plaques in predominantly sun-exposed areas.
Method: A diagnosis of AEGCG was made based on the clinical and histologic picture, and treatment with systemic steroids was initiated. However, while tapering the steroid dose, the patient developed a radiating headache that progressed to temporal arteritis and eventual blindness in the right eye.
Conclusion: There have been only two previous case reports presenting an association between AEGCG and temporal arteritis. This report explores AEGCG and its possible relationship to temporal arteritis along with possible treatment regimens cited in the current literature.

• 出版日期2011-10