BRIGHT LIGHT TREATMENT FOR HIGH-ANXIOUS YOUNG ADULTS: A RANDOMIZED CONTROLLED PILOT STUDY

作者：Youngstedt Shawn D^*; Kline Christopher E; Gin**erg Jay P; Zielinski Mark R; Hardin James W

来源：Depression and Anxiety, 2011, 28(4): 324-332.

DOI：10.1002/da.20784

• phototherapy
• anxiety
• psychic anxiety
• randomized controlled trial
• blood pressure

Background: Available treatments for anxiety have limitations and/or side effects. The aim of this study was to examine the influence of bright light exposure as a treatment in high-anxious young adults. Methods: In an acute exposure study, participants (n = 33) were randomly assigned to 45 min of (1) bright light or (2) placebo. Participants then performed a 5-week study (n = 29). Following a 1-week baseline, participants were randomly assigned to 4 weeks of daily exposure to either (1) bright light (45 min/day) or (2) placebo treatment, initiated <= 1hr after awakening. Before and after the experiment, clinical ratings were conducted with the Hamilton Anxiety Scale (HAM-A), Hamilton Depression Scale, and Clinical Global Impressions scale. Following each week, blood pressure, anxiety (Spielberger State-Trait Anxiety Inventory Y1), depression, mood, sleep, and side effects were assessed. Results: No significant treatment effect was found in the acute exposure study. Likewise, in the 5-week study, no significant treatment effect was found. However, bright light elicited marginally greater reductions in psychic symptoms of the HAM-A (P = .06) and other measures. Conclusions: This pilot study provides little compelling evidence for an anxiolytic effect of bright light in high-anxious young adults. Depression and Anxiety 28:324-332, 2011.

• 出版日期2011-4