Analysis of similarity of RNA secondary structures based on a 2D graphical representation

作者:Li Chun; Xing Lili; Wang Xin
来源:Chemical Physics Letters, 2008, 458(1-3): 249-252.
DOI:10.1016/j.cplett.2008.04.112

摘要

We introduce a 2D graphical representation of RNA secondary structures, which has an important advantage over the existing graphical representations of RNA in being very compact. Then we transform the 2D graph into a numerical characterization that will facilitate quantitative comparisons of RNA secondary structures. The examination of similarities/dissimilarities of a set of RNA secondary structures at the 3'-terminus of nine different viruses illustrates the utility of the approach.

  • 出版日期2008-6-6
  • 单位中国人民解放军海军大连舰艇学院; 渤海大学