Determination of trace levels of acetamide, propanamide, and butyramide in surface and drinking water using gas chromatography-mass spectrometry after derivatization with 9-xanthydrol

作者：Cho Young Hwan; Shin Ho Sang^*

来源：Analytica Chimica Acta, 2013, 787: 111-117.

DOI：10.1016/j.aca.2013.06.013

• Acetamide
• Propanamide
• Butyramide
• Gas chromatography-mass spectrometry
• Xanthydrol derivatization
• Water

A sensitive gas chromatographic mass spectrometric (GC-MS) method has been established for the simultaneous determination of acetamide (AA), propanamide (PA), and butyramide (BA) in surface and drinking water based on derivatization with 9-xanthydrol. Deuterated acrylamide was chosen as the internal standard for analyzing the water sample. The derivatization of AA, PA, and BA was performed directly in water and the reaction conditions (10.0-mM 9-xanthydrol, 0.5-M HCl, 20-min reaction time, and ambient temperature) were established. Under these conditions, the detection limit of the analytes was 0.03 mu g L-1, and the interday relative standard deviation was less than 16% at concentrations of 1.0, 5.0 and 10.0 mu g L-1. The proposed GC-MS method enables the reliable analysis of trace AA, PA, and BA in environmental water.

• 出版日期2013-7-17