Diarylpentanol constituents from the aerial part of Stelleropsis tianschanica

作者:Shi, Lei-Ling; Ma, Guo-Xu; Gao, Hua-Chun; Chen, Quan-Cheng; Yang, Jun-Shan; Jia, Xiao-Guang*; Zhang, Jing*
来源:Journal of Asian Natural Products Research, 2016, 18(9): 885-890.
DOI:10.1080/10286020.2016.1171759

摘要

Five diarylpentanol derivatives including two new compounds stellerasme A (1), stellerasme B (2) were isolated from the aerial parts of Stelleropsis tianschanica. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, CD, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity activity against HeLa and KB cell lines, and compound 1 showed selective activities against HeLa cell line with an IC50 value of 7.4 mu M.