A Concise Total Synthesis of (+/-)-Cassumunin C

作者：Dai, Yihua^*; He, Yazheng; Wang, Yao; Jiang, Huifang; Li, Zhifang; Chen, Weifeng

来源：Synthesis (Germany), 2014, 46(22): 3041-3046.

DOI：10.1055/s-0034-1378557

• aldol condensation
• aromatic propargylation
• Reimer-Tiemann reaction
• lithium aluminum hydride
• natural product

The first concise and efficient total synthesis of (+/-)-cassumunin C has been accomplished with a longest linear sequence of seven steps in 11.7% yield. The key steps involve aromatic propargylation and stereoselective reduction of alkynylphenol to the corresponding (E)-alkenylphenol.

• 出版日期2014-11
• 单位杭州师范大学