A new cytotoxic bufadienolide from Chinese medicine Chansu

作者：Xin Xiu Lan; Lan Rong; Huang Jian; Wang Xiao Jie; Jia Jing Ming^*

来源：Chinese Chemical Letters, 2008, 19(12): 1445-1446.

DOI：10.1016/j.cclet.2008.09.037

• Bufadienolide
• Steroid
• Cytotoxicity
• Chansu

A new cytotoxic bufadienolide was isolated from the traditional Chinese medicine-Chansu. The structure of new compound was elucidated on the basis of spectral methods including 2D NMR. And it showed strong in vitro cytotoxic activity against Hela cells with IC(50) of 8.06 x 10(-2) mmol/L.

• 出版日期2008-12
• 单位北京电子科技职业学院; 沈阳药科大学