Allergic contact eczema to a long-used cosmetic. Methylisothiazolinon, a type IV-allergen

作者：Gaebelein Wissing N^*; Lehmann P; Hofmann S C

来源：Hautarzt, 2015, 66(6): 462-464.

DOI：10.1007/s00105-014-3557-x

• Methylisothiazolinon
• Allergic contact eczema
• Photoallergy
• Type IV sensitization
• Cosmetics

Methylisothiazolinone was permitted in 2004 as preservative in rinse-off and leave-on products by the European cosmetics directive. This led to a dramatic increase in contact eczemas induced by MI in the past few years. Here, we report a patient who developed a spreading contact eczema of the face, neck and proximal arms mimicking a photodermatosis. The reaction was caused by use of a facial ointment that only recently started to contain MI. Type IV-sensitization to MI was verified by patch testing.

• 出版日期2015-6