Denosumab: A novel antiresorptive drug for osteoporosis

作者:Suresh Ernest*; Abrahamsen Bo
来源:Cleveland Clinic Journal of Medicine, 2015, 82(2): 105-114.
DOI:10.3949/ccjm.82a.13173

摘要

Denosumab is a novel antiresorptive drug that has been approved for use as a first-line drug for primary and secondary prevention of osteoporotic fractures. The authors discuss the mechanism of action of denosumab, review the evidence for its efficacy and safety in patients with osteoporosis, and offer recommendations for its use in clinical practice.

  • 出版日期2015-2