Anti-fungal effect of Hevea brasiliensis latex C-serum on Aspergillus niger

作者：Daruliza K M A; Lam K L; Yang K L; Priscilla J T; Sunderasan E; Ong M T^*

来源：European Review for Medical and Pharmacological Sciences, 2011, 15(9): 1027-1033.

• Hevea brasiliensis
• C-serum
• Anti-fungal
• Aspergillus niger
• Brine shrimp lethality test

Objectives: Hevea brasiliensis extract could potentially be employed as a relatively low cost resource for various anti-fungal activities due to the simplicity of latex preparation and the abundance of latex that can be obtained in rubber producing regions. The present study was aimed at examining the species specific anti-fungal property of H. brasilensis latex C-serum against Aspergillus niger.
Results: The results showed that the latex C-serum exerted a specific antifungal activity against Aspergillus niger, but not Candida albicans. Low toxicity of the C-serum was demonstrated in Brine Shrimp Lethality Test (BSLT) with an LC(50) value of 98.4 mg/ml.
Conclusions: Pending further more elaborated investigations, H. brasiliensis latex C-serum, with its species specific anti-fungal and cancer-origin cell line specific anti-proliferation properties, would probably contribute in healthcare in addition to its traditional role in polymer industry.

• 出版日期2011-9