科研之友
微信
新浪微博
Facebook
分享链接
摘要
Lymphoepithelioma, as is well known, is a form of undifferentiated epithelial tumor, which is primarily described in the nasopharynx and characterized by syncytial sheets of malignant epithelial cells with a prominent reactive lymphoid infiltrate in background. A carcinoma that shows similar histological features but arises outside the nasopharynx is called lymphoepithelioma-like carcinoma (LELC). Primary LELC of the renal pelvis is very rare and there is only limited information in the published reports. We managed a case of a 59-year-old man, who presented with asymptomatic gross hematuria for more than one month. MRI showed that right kidney accounted for a soft tissue signal mass with a diameter of 2.3 cm in renal pelvis. He was treated with the Robot assisted Radical resection of the right tumor and was diagnosed with a pT3 NO cMO, the high grade of renal invasive urothelial carcinoma, with predominant Lymphoepithelioma-like carcinoma differentiation. Unlike nasopharyngeal lymphoepithelioma, in situ hybridization analysis of this urinary LELC was negative for the Epstein-Barr virus. Here we report on one more case of primary LELC of the renal pelvis, and review of the published reports, particularly those describing the expression of Epstein-Barr virus.
- 出版日期2017
- 单位南京大学
