Stabilities of Ga-67- and In-111-Labeled Transferrin In Vitro

作者:Ohtake Yosuke*; Maruko Akiko; Kuwahara Yoshikazu; Fukumoto Manabu; Ohkubo Yasuhito
来源:Protein and Peptide Letters, 2009, 16(2): 138-142.

摘要

We attempted to develop a stable radiolabeled transferrin (Tf) useful in experimental studies related to Tf receptor. Ga-67 and In-111 were used as labeling radioisotopes. The results from gel chromatography, dialysis, and electrophoresis showed that In-111-DTPA-Tf was the most stable among the radiolabeled Tfs examined in the present study. In-111-DTPA-Tf was also the most stable radiolabeled transferrin in the blood.

  • 出版日期2009-2