Dihydroboronium derivatives of (S,S)-1,2-bis(t-butylmethylphosphino)ethane as convenient chiral ligand precursors

作者：Miyazaki T; Sugawara M; Danjo H; Imamoto T^*

来源：Tetrahedron Letters, 2004, 45(51): 9341-9344.

DOI：10.1016/j.tetlet.2004.10.119

• (diphosphine)boronium salts
• P-chiral diphosphine
• catecholborane
• Rh-catalyzed asymmetric hydrogenation

Dihydroboroniurn derivatives of (S,S)-1,2-bis(t-butylmethylphosphino)ethane (t-Bu-BisP*) were prepared and used as chiral diphosphine ligand precursors in Rh-catalyzed asymmetric hydrogenation of methyl (Z)-acetamidocinnamate to afford the hydrogenation product in up to 94% enantioselectivity.

• 出版日期2004-12-13