AKAP5 Keeps L-type Channels and NFAT on Their Toes

作者：Navedo Manuel F^*; Hell Johannes W

来源：Cell Reports, 2014, 7(5): 1341-1342.

DOI：10.1016/j.celrep.2014.05.052

In this issue of Cell Reports, Murphy et al. and Dittmer et al. present exciting new insight into the regulation of Ca2+ influx via the L-type Ca2+ channel Ca(v)1.2 and how increased Ca2+ influx translates into localized activation of the nuclear transcription factor NFAT upon depolarization in neurons.

• 出版日期2014-6-12