Development of a fast capillary electrophoresis-time-of-flight mass spectrometry method for the speciation of organotin compounds under separation conditions of high electrical field strengths

作者：Malik Ashok Kumar; Grundmann Marco; Matysik Frank Michael^*

来源：Talanta, 2013, 116: 559-562.

DOI：10.1016/j.talanta.2013.07.025

• Capillary electrophoresis
• Time-of-flight mass spectrometry
• Dibutyltin
• Tributyltin
• Diphenyltin
• Triphenyltin
• Speciation analysis
• Water samples

A novel approach has been developed for the separation of organotin species with capillary electrophoresis hyphenated to time-of-flight mass spectrometry. It has been applied to the development of a method for the determination and speciation of organotin compounds namely, dibutyltin (DBT), tributyltin (TBT), diphenyltin (DPT) and triphenyltin (TPT) in water samples. Experiments were made with a special laboratory constructed CE instrument A non-aqueous buffer system compatible with TOF-MS has been developed using ammonium acetate-acetic acid (50 mM and 1 M) in acetonitrile: methanol (80:20). The total analysis time is less than 3 min for these compounds under the conditions developed. The method has been applied successfully to the determination of these compounds in river water samples. Detection limits of the CE-TOF-MS method were between 1 and 8 x 10(-7) M, and between 2 and 11 x 10(-9) M (0.46 to 3.2 mu g L-1) when used in conjunction with solid phase extraction. The short analysis time as well as good sensitivity and selectivity make it a useful approach for the fast screening of organotin compounds.

• 出版日期2013-11-15