Aromatase inhibitor for treatment of a recurrent abdominal wall endometrioma in a postmenopausal woman

作者：Sasson Isaac E; Taylor Hugh S^*

来源：Fertility and Sterility, 2009, 92(3): 1170.e1.

DOI：10.1016/j.fertnstert.2009.05.071

• Endometriosis
• Endometioma
• Aromatase inhibitor
• menopause
• abdominal wall endometrioma

Objective: Treat an abdominal wall endometrioma in a post-menopausal patient.
Design: Case report.
Setting: Academic medical center.
Patient(s): A post-menopausal women with a large recurrent abdominal wall endometrioma.
Intervention(s): The patient was managed with the combination of an aromatase inhibitor, a progestin, and serial cyst aspiration.
Main Outcome Measure(s): Serum and cyst estradiol levels as well as sonographic demonstration of resolution.
Result(s): Serum and cyst estradiol levels were significantly diminished and the cyst diminished in size.
Conclusion(s): Taken together, this case demonstrates a novel approach for managing and monitoring medical therapy for unusual clinical presentations of endometriosis. Furthermore, it illustrates that endometriotic implants can be a source of circulating estrogen in postmenopausal women, and that this source of estrogen is generated by increased aromatase activity. (Fertil Steril (R) 2009;92:1170.e1-e4.

• 出版日期2009-9