Automatic Model-Based Semantic Registration of Multimodal MRI Knee Data

作者：Xue Ning^*; Doellinger Michael; Fripp Jurgen; Ho Charles P; Surowiec Rachel K; Schwarz Raphael

来源：Journal of Magnetic Resonance Imaging, 2015, 41(3): 633-644.

DOI：10.1002/jmri.24609

• model-based semantic registration
• landmark detection
• knee joint diseases

PurposeTo propose a robust and automated model-based semantic registration for the multimodal alignment of the knee bone and cartilage from three-dimensional (3D) MR image data.
Materials and MethodsThe movement of the knee joint can be semantically interpreted as a combination of movements of each bone. A semantic registration of the knee joint was implemented by separately reconstructing the rigid movements of the three bones. The proposed method was validated by registering 3D morphological MR datasets of 25 subjects into the corresponding T2 map datasets, and was compared with rigid and elastic methods using two criteria: the spatial overlap of the manually segmented cartilage and the distance between the same landmarks in the reference and target datasets.
ResultsThe mean Dice Similarity Coefficient (DSC) of the overlapped cartilage segmentation was increased to 0.680.1 (mean +/- SD) and the landmark distance was reduced to 1.3 +/- 0.3 mm after the proposed registration method. Both metrics were statistically superior to using rigid (DSC: 0.59 +/- 0.12; landmark distance: 2.1 +/- 0.4 mm) and elastic (DSC: 0.64 +/- 0.11; landmark distance: 1.5 +/- 0.5 mm) registrations.
ConclusionThe proposed method is an efficient and robust approach for the automated registration between morphological knee datasets and T2 MRI relaxation maps. J. Magn. Reson. Imaging 2015;41:633-644.

• 出版日期2015-3
• 单位CSIRO