A Programmable Implantable Microstimulator SoC With Wireless Telemetry: Application in Closed-Loop Endocardial Stimulation for Cardiac Pacemaker

作者：Lee Shuenn Yuh^*; Su Mario YuCheng; Liang Ming Chun; Chen You Yin; Hsieh Cheng Han; Yang Chung Min; Lai Hsin Yi; Lin Jou Wei; Fang Qiang

来源：IEEE Transactions on Biomedical Circuits and Systems, 2011, 5(6): 511-522.

DOI：10.1109/TBCAS.2011.2177661

• Endocardial stimulation
• pacemaker
• power management
• programmable implantable stimulator
• wireless telemetry

A low-power, wireless, and implantable microstimulator system on chip with smart powering management, immediate neural signal acquisition, and wireless rechargeable system is proposed. A system controller with parity checking handles the adjustable stimulus parameters for the stimulated objective. In the current paper, the rat's intra-cardiac electrogram is employed as the stimulated model in the animal study, and it is sensed by a low-voltage and low-power monitoring analog front end. The power management unit, which includes a rectifier, battery charging and detection, and a regulator, is used for the power control of the internal circuits. The stimulation data and required clock are extracted by a phase-locked-loop-based phase shift keying demodulator from an inductive AC signal. The full chip, which consumes 48 mu W only, is fabricated in a TSMC 0.35 mu m 2P4M standard CMOS process to perform the monitoring and pacing functions with inductively powered communication in the in vivo study.

• 出版日期2011-12