Post-Traumatic Stress Disorder Predicts Future Weight Change in the Millennium Cohort Study

作者：LeardMann Cynthia A^*; Woodall Kelly A; Littman Alyson J; Jacobson Isabel G; Boyko Edward J; Smith Besa; Wells Timothy S; Crum Cianflone Nancy F

来源：Obesity, 2015, 23(4): 886-892.

DOI：10.1002/oby.21025

ObjectiveTo prospectively examine the association between post-traumatic stress disorder (PTSD) and weight change.
MethodsLongitudinal analysis techniques were used to examine data (2001-2008) from Millennium Cohort Study participants, consisting of U.S. service members and veterans. Using the PTSD Checklist-Civilian Version, PTSD was assessed as none, resolved, new onset, or persistent. Subsequent weight change was assessed as stable (loss or gain), >3% weight loss, >3% but <10% weight gain, and 10% weight gain.
ResultsOf the 38,352 participants, 2391 (6.2%) had PTSD (838 resolved, 1024 new onset, and 529 persistent), and 11% of participants subsequently had 10% weight gain. In multivariable models, PTSD was associated with higher odds of 10% weight gain (new onset OR: 1.44 [95% CI: 1.20-1.73]; persistent OR: 1.51 [CI: 1.17-1.96]; resolved OR: 1.30 [CI: 1.05-1.60]) compared with those without PTSD. New-onset and persistent PTSD were also associated with higher odds of >3% weight loss (OR: 1.41 [CI: 1.17-1.71]; OR: 1.42 [CI: 1.09-1.86], respectively).
ConclusionsPTSD is independently associated with a higher risk of weight gain and loss, the former of which leads to a higher prevalence of overweight and obesity and a higher risk of comorbidities associated with excessive body adiposity.

• 出版日期2015-4