Novel application of high-dose rate brachytherapy for severe, recalcitrant palmoplantar pustulosis

作者：Timerman D; Devlin P M; Nambudiri V E; Wright N A; Vleugels R A; Clark R A; Kupper T S; Merola J F; Patel M^*

来源：Clinical and Experimental Dermatology, 2016, 41(5): 498-501.

DOI：10.1111/ced.12803

Palmoplantar pustulosis (PPP) is a chronic pustular dermatitis of the palms and soles, which is frequently associated with significant pruritus and pain, often limiting daily activities. We present the case of a 36-year-old man with severe PPP who had treatment failure with multiple medical therapies but showed marked improvement with high-dose rate brachytherapy. Brachytherapy has the advantage of providing a conformal dose distribution over complex curved surfaces, such as the foot and ankle. Our observations suggest that brachytherapy may be a well-tolerated treatment option for patients with severe, refractory PPP.

• 出版日期2016-7
• 单位MIT