Aminated Cellulose Nanofibers for Selective Removal of Endotoxins from Protein Solutions

作者：Sakata Masayo^*; Sakamoto Towako; Shimizu Megumi; Harada Risa; Nakamura Daisuke; Maeda Yuki

来源：Chemistry Letters, 2017, 46(2): 194-196.

DOI：10.1246/cl.160996

• Aminated cellulose nanofiber
• Removal of endotoxin
• Adsorbent

Aminated cellulose nanofibers (CNFs) were prepared by attaching diaminoethane or polyethyleneimine onto microfibrillated CNFs and used for the selective removal of endotoxins (lipopolysaccharides; LPSs) from acidic protein solutions. The adsorption of the LPSs was measured at pH 7.0 and an ionic strength (mu) of 0.2. The diaminoethane-immobilized CNFs (amino group content of 0.9 meq g(-1)) selectively removed LPSs from protein solutions (isoelectric point (pI) 4.9-11.0) without adsorption of the proteins.

• 出版日期2017-2