Melanotic Neuroectodermal Tumor of Infancy Arising in the Temporal Bone

作者：Zhang, Jian-guo; Zhao, Rui-jiao^*; Kong, Ling-fei

来源：Journal of Child Neurology, 2015, 30(5): 631-634.

DOI：10.1177/0883073813494477

• benign neoplasm
• melanotic neuroectodermal tumor of infancy
• temporal bone

Melanotic neuroectodermal tumor of infancy is a rare melanin-containing neoplasm with locally aggressive and rapid expansile growth, usually involving the maxilla, skull, and mandible of early infancy. Radical surgery is critical for a long-term outcome. We present a case of 14-month-old girl with rapid-growing subcutaneous mass arising in the right temporal bone and extending intracranially on computed tomographic scan. Radical surgery was performed. A brownish-black tumor composed of large pigmented epithelioid cells, positive for cytokeratins and HMB-45, and nests of small neuroblast-like cells positive for neuron-specific enolase and synaptophysin, was diagnosed as melanotic neuroectodermal tumor of infancy. The patient remained well without evidence of recurrence for 1 year after surgery. Clinicopathological features, management alternatives and outcome were discussed.

• 出版日期2015-4
• 单位河南省人民医院