摘要
The highly efficient, regioselective, and enantioselective transfer hydrogenation of alpha-keto ketimines and reductive amination of diketones by Bronsted acid catalysis is described. A series of chiral a-amino ketones is prepared in high yields (up to >99%), excellent regioselectivities (up to >99:1), and enantioselectivities (up to 98% ee). This method has broad substrate scope.
- 出版日期2015-8-7
- 单位西南大学