A stereoselective cyclization to carbafuranose derivatives starting from 1,4-bis-epoxides

作者:Leung LMH*; Boydell AJ; Gibson V; Light ME; Linclau B
来源:Organic Letters, 2005, 7(23): 5183-5186.
DOI:10.1021/ol052009h

摘要

A concise synthesis of highly functionalized cyclopentane derivatives via a Brook rearrangement mediated stereoselective linchpin cyclization reaction involving tert-butyldimethylsilyl-1,3-dithianyllithium and homochiral 1,4-bis-epoxides is described.

  • 出版日期2005-11-10