An expedient route to p-tert-butylthiacalix[4]arene 1,3-diethers via Mitsunobu reactions

作者：Bitter I^*; Csokai V

来源：Tetrahedron Letters, 2003, 44(11): 2261-2265.

DOI：10.1016/S0040-4039(03)00285-5

• thiacalix[4]arenes
• O-alkylation
• mitsunobu reaction

Regioselective distal dialkylation of p-tert-butylthiacalix[4]arene with alcohols was performed under the Mitsunobu protocol using the DEAD/TPP system. The method provides a versatile tool for obtaining 1,3-diethers with different functional groups in the alkyl chains.

• 出版日期2003-3-10