Aneurysms of Medium-Sized Arteries in Marfan Syndrome

作者：Awais Mazen^*; Williams David M; Deeb G Michael; Shea Michael J

来源：Annals of Vascular Surgery, 2013, 27(8): 1188.e5.

DOI：10.1016/j.avsg.2012.12.002

Marfan syndrome is a relatively common connective tissue disorder that causes skin, ocular, skeletal, and cardiovascular abnormalities. High morbidity and mortality occur with aortic aneurysm and dissection. Other large-artery aneurysms, including carotid, subclavian, and iliac artery aneurysms, have also been associated with Marfan syndrome. It is not clear whether small- to medium-sized artery aneurysms are associated with Marfan syndrome. This report describes 4 patients with Marfan syndrome who have associated small-to medium-sized artery aneurysms with several complications. Additional investigations are needed to determine whether Marfan syndrome can cause small-to medium-sized artery aneurysms and how patients with these aneurysms should be treated.

• 出版日期2013-11