Facile preparation of bicyclo[2.2.2]octenone derivatives via Diels-Alder cycloadditions of in situ-generated masked o-benzoquinones

作者：Kalogiros Christos; Hadjiarapoglou Lazaros P^*

来源：Tetrahedron, 2011, 67(18): 3216-3225.

DOI：10.1016/j.tet.2011.03.018

• 2,2-Dimethoxycyclohexa-3,5-dienone
• retro-Diels-Alder/Diels-Alder
• cycloaddition
• Masked o-benzoquinone
• Phenol oxidation

Diels-Alder cycloadditions of in situ-generated, substituted 2,2-dimethoxycyclohexa-3,5-dienones with olefinic dienophiles resulted in the development of an efficient method for the preparation of highly functionalized bicyclo[2.2.2]oct-5-en-2-ones with good to excellent yields.

• 出版日期2011-5-6