A Predictably Selective Nitration of Olefin with Fe(NO3)(3) and TEMPO

作者:Naveen Togati; Maity Soham; Sharma Upendra; Maiti Debabrata*
来源:Journal of Organic Chemistry, 2013, 78(12): 5949-5954.
DOI:10.1021/jo400598p

摘要

Ferric nitrate with catalytic TEMPO has been identified as a useful reagent for regio- and stereoselective nitration of a wide variety of aromatic, aliphatic, and heteroaromatic olefins. This reaction provided nitroolefins in preparatively useful yields with excellent E-selectivity. Due to its mild nature and operational simplicity, the present protocol is expected to find application in synthetic setup.

  • 出版日期2013-6-21