Amperometric glucose biosensor based on Prussian blue-multiwall carbon nanotubes composite and hollow PtCo nanochains

作者：Che, Xin; Yuan, Ruo^*; Chai, Yaqin; Li, Jingjing; Song, Zhongju; Li, Wenjuan

来源：Electrochimica Acta, 2010, 55(19): 5420-5427.

DOI：10.1016/j.electacta.2010.04.091

• Prussian blue
• Carbon nanotubes
• Hollow PtCo nanochains
• Nafion
• Glucose

In this paper, a novel glucose biosensor was developed based on immobilizing glucose oxidase (GOD) on Prussian blue-multiwall carbon nanotubes (PB@MWNTs) composite and hollow PtCo (H-PtCo) nanochains modified electrode. The PB@MWNTs/H-PtCo membrane showed good biocompatibility, large surface-to-volume ratio and excellent electron-conductive ability. The successful fabrication of the PB@MWNTs composite synthesized with MWNTs as a template and Fe(III)-reducer were characterized by UV-vis absorption spectroscopy, Fourier transform infrared (FTIR) spectrometry and transmission electron microscopy (TEM). The hollow PtCo nanochains were also characterized by TEM and X-ray photoelectron spectroscopy (XPS). The response of the biosensor towards glucose under the optimized conditions, as investigated by chronoamperometry, is linear from 3.0 mu M to 3.6 mM, with a low detection limit of 0.85 mu M (S/N = 3) and a high sensitivity 21 mA M-1 cm(-2). Moreover, the biosensor exhibits strong anti-interferent ability, good reproducibility and excellent stability.

• 出版日期2010-7-30
• 单位西南大学