Deep cerebral vein expansion with metabolic and neurocognitive recovery in Sturge-Weber syndrome

作者：John Flora; Maqbool Mohsin; Jeong Jeong won; Agarwal Rajkumar; Behen Michael E; Juhasz Csaba^*

来源：Annals of Clinical and Translational Neurology, 2018, 5(4): 502-506.

DOI：10.1002/acn3.546

We present longitudinal imaging data of a child with Sturge-Weber syndrome (SWS). At age 8 months, 3 weeks after initial seizures and prolonged motor deficit, MRI showed extensive right hemispheric SWS involvement with severe glucose hypometabolism on PET. She was treated with levetiracetam and aspirin. Follow-up imaging at age 29 months showed a robust interval expansion of enlarged deep medullary veins throughout the affected hemisphere along with a dramatic recovery of hemispheric metabolism and normalized neurocognitive functioning. These findings demonstrate a robust, multilobar hemispheric remodeling of deep venous collaterals that likely contributed to reversal of initial metabolic and neurocognitive deficits.

• 出版日期2018-4