The serum level of interleukin-6 in patients with intellectual disability and refractory epilepsy

作者：Lehtimaki Kai A^*; Liimatainen Suvi; Peltola Jukka; Arvio Maria

来源：Epilepsy Research, 2011, 95(1-2): 184-187.

DOI：10.1016/j.eplepsyres.2011.03.004

• Cytokine
• Epilepsy
• Interleukin-6
• Seizure frequency
• Intellectual disability

We aimed to study the influences of active epilepsy and intellectual disability (ID) on the serum interleukin-6 (IL-6) by determining levels in 74 patients with developmental disorder with epilepsy and 63 healthy controls. The patients showed significantly higher IL-6 levels than the controls (4.1 +/- 4.5 pg/ml vs. 2.1 +/- 1.0 pg/ml; p < 0.001). High seizure frequency and severe intellectual disability emerged as predictors for elevated serum levels of IL-6.

• 出版日期2011-6