An assessment of R&D productivity in the pharmaceutical industry

作者:Dimitri Nicola*
来源:Trends in Pharmacological Sciences, 2011, 32(12): 683-685.
DOI:10.1016/j.tips.2011.09.005

摘要

Recent reports suggest that R&D productivity in the pharmaceutical industry can be strengthened by reducing costs both in the early phase and, mostly, in the clinical phase of drug discovery. However, a cost benefit probabilistic analysis reveals that despite high costs, the clinical phase shows healthy productivity, whereas the early phase, particularly lead optimization, exhibits very low productivity.

  • 出版日期2011-12