科研之友
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摘要
The possibility of performing reliable cancer diagnosis even before any symptoms of disease appears is crucial for increasing therapeutic treatment success and patient survival rates. Herein, an ultrasensitive colorimetric sandwich sensor for vascular endothelial growth factor (VEGF) detection is introduced. The peroxidase-like DNAzyme catalyzes the oxidation of 2,2'-azino-bis(3-ethylbenzothiazoline)-6-sulfonic acid, which generates a blue-green colorimetric signal. This method can detect VEGF at a concentration as low as 10 nM. This strategy will be a promising tool for bioanalytical and clinical applications.
- 出版日期2016
- 单位江苏省原子医学研究所; 南京医科大学
