科研之友
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摘要
A new approach to 2,6-disubstituted tetrahydropyrans by a tandem cross-metathesis/iodocyclisation reaction has been developed. The stereochemical outcome of the cyclisation reactions has been studied for different substrates. This sequence has allowed the preparation of a series of cis- and trans-2,6-disubstituted analogues of the tetrahydropyran subunit of bistramide A.
- 出版日期2008-2
